I've been in San Francisco for more than 20 years, and have lived in the same neighborhood all that time. I love that SF is a city with all the cool, interesting, exasperating city stuff; and that I get to live in a place where the grocer says "Good morning, Evie" to me every day, and the boys (that is, the grown up men) gather most days in front of the cafe to gossip and talk sports and politics (and usually let me join them).
I've worked for myself since 2000, and love the not having a boss thing. My work is not particularly glamourous--I do accounting for nonprofits and small business--but it does suit me, even if I hate to admit it; and I feel very lucky that I actually enjoy working with nearly everyone I work closely with.*
*A friend recently told me that the rule about not ending a sentence with a preposition has been rescinded. I'm not entirely comfortable with the idea, but I'm working on it--as you can see.